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A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma

20 Mar 2019

Abstract excerpt

Low-passage, serum-free cell lines cultured from patient tumour tissue are the gold-standard for preclinical studies and cellular investigations of glioblastoma (GBM) biology, yet entrenched, poorly-representative cell line models are still widely used, compromising the significance of much GBM research. We submit that greater adoption of these critical resources will be promoted by the provision of a...

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PMID: 30894629
DOI: 10.1038/s41598-019-41277-z

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