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The Human Glioblastoma Cell Culture Resource: Validated Cell Models Representing All Molecular Subtypes

15 Aug 2015

Abstract excerpt

Glioblastoma (GBM) is the most frequent and malignant form of primary brain tumor. GBM is essentially incurable and its resistance to therapy is attributed to a subpopulation of cells called glioma stem cells (GSCs). To meet the present shortage of relevant GBM cell (GC) lines we developed a library of annotated and validated cell lines derived from surgical samples of GBM patients, maintained under conditions to...

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PMID: 26629530
DOI: 10.1016/j.ebiom.2015.08.026

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