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Article

Parkinson's disease-related gene variants influence pre-mRNA splicing processes.

Neurobiology of aging - 1 Nov 2016

Gaweda-Walerych K, Mohagheghi F, Zekanowski C, Buratti E

Abstract excerpt

We have analyzed the impact of Parkinson's disease (PD)-related genetic variants on splicing using dedicated minigene assays. Out of 14 putative splicing variants in 5 genes (PINK1, [PTEN induced kinase 1]; LRPPRC, [leucine-rich pentatricopeptide repeat containing protein]; TFAM, [mitochondrial transcription factor A]; PARK2, [parkin RBR E3 ubiquitin protein ligase]; and HSPA9, [heat shock protein family A...

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Source

Identifiers

PMID: 27574110
DOI: 10.1016/j.neurobiolaging.2016.07.014

Genes

HSPA9
PINK1
PTEN
TFAM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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