Article
TRPA1 and TRPV1 contribute to iodine antiseptics-associated pain and allergy.
EMBO reports - 1 Oct 2016
Su Deyuan, Zhao Hong, Hu Jinsheng, Tang Dan, Cui Jianmin, Zhou Ming, Yang Jian, Wang Shu
Abstract excerpt
Iodine antiseptics exhibit superior antimicrobial efficacy and do not cause acquired microbial resistance. However, they are underused in comparison with antibiotics in infection treatments, partly because of their adverse effects such as pain and allergy. The cause of these noxious effects is not fully understood, and no specific molecular targets or mechanisms have been discovered. In this study, we show that...
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