Article
Zebrafish TRPA1 channels are required for chemosensation but not for thermosensation or mechanosensory hair cell function.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Oct 2008
Prober David A, Zimmerman Steven, Myers Benjamin R, McDermott Brian M, Kim Seok-Hyung, Caron Sophie, Rihel Jason, Solnica-Krezel Lilianna, Julius David, Hudspeth A J, Schier Alexander F
Abstract excerpt
Transient receptor potential (TRP) ion channels have been implicated in detecting chemical, thermal, and mechanical stimuli in organisms ranging from mammals to Caenorhabditis elegans. It is well established that TRPA1 detects and mediates behavioral responses to chemical irritants. However, the role of TRPA1 in detecting thermal and mechanical stimuli is controversial. To further clarify the functions of TRPA1...
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