Article
Copy number gain of chromosome 3q is a recurrent event in patients with intraductal papillary mucinous neoplasm (IPMN) associated with disease progression.
Oncotarget - 15 Nov 2016
Durante Sandra, Vecchiarelli Silvia, Astolfi Annalisa, Grassi Elisa, Casadei Riccardo, Santini Donatella, Panzacchi Riccardo, Ricci Claudio, Serravalle Salvatore, Tarantino Giuseppe, Falconi Mirella, Teti Gabriella, Indio Valentina, Pession Andrea, Minni Francesco, Biasco Guido, Di Marco Mariacristina
Abstract excerpt
BACKGROUND: Intraductal papillary mucinous neoplasm (IPMN) is the most common cystic preneoplastic lesion of pancreatic cancer. We used an approach coupling high resolution cytogenetic analysis (Affymetrix Oncoscan FFPE Array) with clinically-oriented bioinformatic interpretation of data to understand the most relevant alterations of precursor lesions at different stages to identify new diagnostic markers....
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