Article
Micrococcin P1 - A bactericidal thiopeptide active against Mycobacterium tuberculosis.
Tuberculosis (Edinburgh, Scotland) - 1 Sept 2016
Degiacomi Giulia, Personne Yoann, Mondésert Guillaume, Ge Xueliang, Mandava Chandra Sekhar, Hartkoorn Ruben C, Boldrin Francesca, Goel Pavitra, Peisker Kristin, Benjak Andrej, Barrio Maria Belén, Ventura Marcello, Brown Amanda C, Leblanc Véronique, Bauer Armin, Sanyal Suparna, Cole Stewart T, Lagrange Sophie, Parish Tanya, Manganelli Riccardo
Abstract excerpt
The lack of proper treatment for serious infectious diseases due to the emergence of multidrug resistance reinforces the need for the discovery of novel antibiotics. This is particularly true for tuberculosis (TB) for which 3.7% of new cases and 20% of previously treated cases are estimated to be caused by multi-drug resistant strains. In addition, in the case of TB, which claimed 1.5 million lives in 2014, the...
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