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Matrix metalloproteinase-1 and matrix metalloproteinase-12 gene polymorphisms and the outcome of coronary artery disease.

Coronary artery disease - 1 Jan 2011

Jguirim-Souissi Imen, Jelassi Awatef, Slimani Afef, Addad Faouzi, Hassine Majed, Hamda Khaldoun Ben, Najah Mohamed, Maatouk Faouzi, Rouis Mustapha, Slimane Mohamed Naceur

Abstract excerpt

OBJECTIVES: In this study, we investigated the association between matrix metalloproteinase-1 (MMP-1) G-1607GG, MMP-12 A-82G and MMP-12 A1082G genotypes and haplotypes and the prognosis of coronary artery disease (CAD). METHODS: A total of 129 Tunisian patients with CAD were followed prospectively for a median of 2.5 years. Genotypes were determined by a PCR-based restriction fragment length polymorphism. Two...

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Identifiers

PMID: 21606841
DOI: 10.1097/MCA.0b013e3283478d40

Genes

CAD

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