Article
Disease-Homologous Mutation in the Cation Diffusion Facilitator Protein MamM Causes Single-Domain Structural Loss and Signifies Its Importance.
Scientific reports - 23 Aug 2016
Barber-Zucker Shiran, Uebe René, Davidov Geula, Navon Yotam, Sherf Dror, Chill Jordan H, Kass Itamar, Bitton Ronit, Schüler Dirk, Zarivach Raz
Abstract excerpt
Cation diffusion facilitators (CDF) are highly conserved, metal ion efflux transporters that maintain divalent transition metal cation homeostasis. Most CDF proteins contain two domains, the cation transporting transmembrane domain and the regulatory cytoplasmic C-terminal domain (CTD). MamM is a magnetosome-associated CDF protein essential for the biomineralization of magnetic iron-oxide particles in...
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