Article
Recent progress in structure-function analyses of Nramp proton-dependent metal-ion transporters.
Biochemistry and cell biology = Biochimie et biologie cellulaire - 1 Dec 2006
Courville P, Chaloupka R, Cellier M F M
Abstract excerpt
The natural resistance-associated macrophage protein (Nramp) homologs form a family of proton-coupled transporters that facilitate the cellular absorption of divalent metal ions (Me2+, including Mn2+, Fe2+, Co2+, and Cd2+). The Nramp, or solute carrier 11 (SLC11), family is conserved in eukaryotes and bacteria. Humans and rodents express 2 parologous genes that are associated with iron disorders and immune...
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