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Article

Extracellular Vesicles from Metastatic Rat Prostate Tumors Prime the Normal Prostate Tissue to Facilitate Tumor Growth.

Scientific reports - 23 Aug 2016

Halin Bergström Sofia, Hägglöf Christina, Thysell Elin, Bergh Anders, Wikström Pernilla, Lundholm Marie

Abstract excerpt

Accumulating data indicates that tumor-derived extracellular vesicles (EVs) are responsible for tumor-promoting effects. However, if tumor EVs also prepare the tumor-bearing organ for subsequent tumor growth, and if this effect is different in low and high malignant tumors is not thoroughly explored. Here we used orthotopic rat Dunning R-3327 prostate tumors to compare the role of EVs from fast growing and...

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Identifiers

PMID: 27550147
DOI: 10.1038/srep31805
PMCID: PMC4994101

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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