Article
Progressive epithelial to mesenchymal transitions in ARCaP E prostate cancer cells during xenograft tumor formation and metastasis.
The Prostate - 1 Apr 2010
He Hui, Yang Xiaojian, Davidson Alec J, Wu Daqing, Marshall Fray F, Chung Leland W K, Zhau Haiyen E, Wang Ruoxiang
Abstract excerpt
BACKGROUND: The mechanism of epithelial to mesenchymal transition (EMT) could be adopted by tumor cells for migration and invasion. We have reported that ARCaP(E) human prostate cancer cells undergo EMT-like changes during xenograft growth in athymic mice. METHODS: In this report, we assessed the extent of EMT by tracking changes in cloned ARCaP(E) cells expressing red fluorescence protein during successive...
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