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Article

Tumor extracellular vesicles drive metastasis (it's a long way from home)

28 Jul 2021

Abstract excerpt

Among a plethora of functions, extracellular vesicles released by primary tumors spread in the organism and reach distant organs where they can induce the formation of a premetastatic niche. This constitutes a favorable microenvironment for circulating tumor cells which facilitates their seeding and colonization. In this review, we describe the journey of extracellular vesicles (EVs) from the primary tumor to the...

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PMID: 34761175
DOI: 10.1096/fba.2021-00079

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