Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epithelial to mesenchymal transition (EMT) in human prostate cancer: lessons learned from ARCaP model.

Clinical & experimental metastasis - 1 Jan 2008

Zhau Haiyen E, Odero-Marah Valerie, Lue Hui-Wen, Nomura Takeo, Wang Ruoxiang, Chu Gina, Liu Zhi-Ren, Zhou Binhua P, Huang Wen-Chin, Chung Leland W K

Abstract excerpt

Androgen refractory cancer of the prostate (ARCaP) cells contain androgen receptor (AR) and synthesize and secrete prostate specific antigen (PSA). We isolated epithelia-like ARCaP(E) from parental ARCaP cells and induced them to undergo epithelial-mesenchymal transition (EMT) by exposing these cells to soluble factors including TGFbeta1 plus EGF, IGF-1, beta2-microglobulin (beta2-m), or a bone microenvironment....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Neoplasms
Share to Epithelial Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mesoderm

Share to Neoplasm Metastasis

Share to Prostatic Neoplasms

Share to RANK Ligand

Share to Receptors, Androgen

Share to Tumor Cells, Cultured

Source

Open in PubMed Open full text

Identifiers

PMID: 18535913
DOI: 10.1007/s10585-008-9183-1
PMCID: PMC3050737

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epithelial to mesenchymal transition (EMT) in human prostate cancer: lessons learned from ARCaP model.PMID 18535913Read ↗

Role of Epithelial Mesenchymal Transition in Prostate TumorigenesisSemantic proximity Read ↗

Progressive epithelial to mesenchymal transitions in ARCaP E prostate cancer cells during xenograft tumor formation and metastasis.Semantic proximity Read ↗

Epithelial-mesenchymal-transition regulators in prostate cancer: Androgens and beyond.Semantic proximity Read ↗

RANK-mediated signaling network and cancer metastasis.Semantic proximity Read ↗

Epidermal Growth Factor Is Essential for the Maintenance of Novel Prostate Epithelial Cells Isolated From Patient-Derived OrganoidsSemantic proximity Read ↗

Epithelial-mesenchymal transition in prostatic disease.Semantic proximity Read ↗

A molecular portrait of epithelial–mesenchymal plasticity in prostate cancer associated with clinical outcomeSemantic proximity Read ↗

SFRP2 Overexpression Induces an Osteoblast-like Phenotype in Prostate Cancer Cells.Semantic proximity Read ↗

Markers of epithelial-to-mesenchymal transition reflect tumor biology according to patient age and Gleason score in prostate cancer.Semantic proximity Read ↗

Targeting the triad: phenotypic plasticity, tumor microenvironment and bone microenvironment in prostate cancer bone-metastatic events.Semantic proximity Read ↗

RANK- and c-Met-mediated signal network promotes prostate cancer metastatic colonizationSemantic proximity Read ↗

Androgen receptor activation stabilizes a hybrid epithelial/mesenchymal phenotype in presence of Notch-Jagged signaling.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.