Article
Exosomes confer pro-survival signals to alter the phenotype of prostate cells in their surrounding environment.
Oncotarget - 22 Mar 2016
Hosseini-Beheshti Elham, Choi Wendy, Weiswald Louis-Bastien, Kharmate Geetanjali, Ghaffari Mazyar, Roshan-Moniri Mani, Hassona Mohamed D, Chan Leslie, Chin Mei Yieng, Tai Isabella T, Rennie Paul S, Fazli Ladan, Tomlinson Guns Emma S
Abstract excerpt
Prostate cancer (PCa) is the most frequently diagnosed cancer in men. Current research on tumour-related extracellular vesicles (EVs) suggests that exosomes play a significant role in paracrine signaling pathways, thus potentially influencing cancer progression via multiple mechanisms. In fact, during the last decade numerous studies have revealed the role of EVs in the progression of various pathological...
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