Article
Extracellular vesicles released by mesenchymal-like prostate carcinoma cells modulate EMT state of recipient epithelial-like carcinoma cells through regulation of AR signaling.
Cancer letters - 1 Dec 2017
El-Sayed Ihsan Y, Daher Ahmad, Destouches Damien, Firlej Virginie, Kostallari Enis, Maillé Pascale, Huet Eric, Haidar-Ahmad Nathaline, Jenster Guido, de la Taille Alexandre, Abou Merhi Raghida, Terry Stéphane, Vacherot Francis
Abstract excerpt
Extracellular vesicles released from cancer cells may play an important role in cancer progression by shuttling oncogenic information into recipient cells. However, our knowledge is still fragmentary and there remain numerous questions regarding the mechanisms at play and the functional consequences of these interactions. We have recently established a mesenchymal-like prostate cancer cell line (22Rv1/CR-1;...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.