Article
CD4+ cell-derived interleukin-17 in a model of dysregulated, Borrelia-induced arthritis.
Pathogens and disease - 1 Oct 2016
Hansen Emily S, Johnson Megan E, Schell Ronald F, Nardelli Dean T
Abstract excerpt
Lyme borreliosis, which is caused in the United States by the spirochete Borrelia burgdorferi, may manifest as different arrays of signs, symptoms and severities between infected individuals. Recent studies have indicated that particularly severe forms of Lyme borreliosis in humans are associated with an increased Th17 response. Here, we hypothesized that a murine model combining the dysregulated immune response...
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