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Article

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17.

Nature immunology - 1 Nov 2005

Park Heon, Li Zhaoxia, Yang Xuexian O, Chang Seon Hee, Nurieva Roza, Wang Yi-Hong, Wang Ying, Hood Leroy, Zhu Zhou, Tian Qiang, Dong Chen

Abstract excerpt

Interleukin 17 (IL-17) has been linked to autoimmune diseases, although its regulation and function have remained unclear. Here we have evaluated in vitro and in vivo the requirements for the differentiation of naive CD4 T cells into effector T helper cells that produce IL-17. This process requir...

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Share to Antigens, Differentiation, T-Lymphocyte
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16200068
DOI: 10.1038/ni1261
PMCID: PMC1618871

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16200068-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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