<i>Borrelia burgdorferi</i> peptidoglycan is a persistent antigen in patients with Lyme arthritis

Abstract excerpt

Significance Lyme disease, caused by the spirochete Borrelia burgdorferi , is the most common vector-borne disease in North America. If early infection is untreated, it can result in late-stage manifestations, including arthritis. Although antibiotics are generally effective at all stages of the disease, arthritis may persist in some patients for months to several years despite oral and intravenous antibiotic...

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