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Article

Association of DYRK1A polymorphisms with sporadic Parkinson's disease in Chinese Han population.

Neuroscience letters - 6 Oct 2016

Cen Luan, Xiao Yousheng, Wei Lei, Mo Mingshu, Chen Xiang, Li Shaomin, Yang Xingling, Huang Qinghui, Qu Shaogang, Pei Zhong, Xu Pingyi

Abstract excerpt

α-Synuclein plays important roles in the development of Parkinson's disease (PD) pathologies. The dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) has a wide range of phosphorylation targets including α-synuclein. Posphorylated α-synuclein is more neurotoxic to dopamine (DA) neurons, but little is known about the genetic variation of DYRK1A in patients with PD. The present investigation...

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Identifiers

PMID: 27546826
DOI: 10.1016/j.neulet.2016.08.022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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