SNCA rs356219 variant increases risk of sporadic Parkinson's disease in ethnic Chinese.

doi:10.1002/ajmg.b.32143

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Article

SNCA rs356219 variant increases risk of sporadic Parkinson's disease in ethnic Chinese.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jul 2013

Li Nan-Nan, Mao Xue-Ye, Chang Xue-Li, Zhao Dong-Mei, Zhang Jin-Hong, Liao Qiao, Yu Wen-Juan, Tan Eng-King, Peng Rong

Abstract excerpt

Alpha-synuclein gene (SNCA) polymorphisms have been associated with Parkinson's disease (PD). A recently published genome-wide association study (GWAS) meta-analysis from the USA and Europe found a strong association between SNCA rs356219 and PD. Considering the population-specific heterogeneity, we investigated the role of SNCA rs356219 as PD susceptibility in a large Han Chinese population of 685 patients and...

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Genetic Predisposition to Disease

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PMID: 23737253
DOI: 10.1002/ajmg.b.32143

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SNCA

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