Article
SNP rs356219 of the α-synuclein (SNCA) gene is associated with Parkinson's disease in a Chinese Han population.
Parkinsonism & related disorders - 1 Jun 2012
Pan Fenghua, Dong Hairong, Ding Haixia, Ye Min, Liu Weiguo, Wu Yanfeng, Zhang Xueling, Chen Zhuoyou, Luo Yang, Ding Xinsheng
Abstract excerpt
BACKGROUND: Over the last decades, increasing knowledge about the genetic architecture of Parkinson's disease(PD) has provided novel insights into the pathogenesis of the disorder. Recently, several studies in different populations have found a strong association between idiopathic PD and the single-nucleotide polymorphism (SNP) rs356219, which is located in the 3'UTR of the SNCA gene. In this study, we aimed to...
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