Article
Mitochondrial dysfunction in Parkinson's disease.
Journal of neurochemistry - 1 Oct 2016
Bose Anindita, Beal M Flint
Abstract excerpt
Parkinson's disease (PD) is the second most common neurodegenerative disease. About 2% of the population above the age of 60 is affected by the disease. The pathological hallmarks of the disease include the loss of dopaminergic neurons in the substantia nigra and the presence of Lewy bodies that are made of α-synuclein. Several theories have been suggested for the pathogenesis of PD, of which mitochondrial...
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