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The Parkinson Disease Mitochondrial Hypothesis

11 Mar 2015

Abstract excerpt

Parkinson's disease is a common, adult-onset neurodegenerative disorder whose pathogenesis is still under intense investigation. Substantial evidence from postmortem human brain tissue, genetic- and toxin-induced animal and cellular models indicates that mitochondrial dysfunction plays a central role in the pathophysiology of the disease. This review discusses our current understanding of Parkinson's...

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Share to Mitochondrial Function and Pathology
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PMID: 25761946
DOI: 10.1177/1073858415574600

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