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Unravelling mitochondrial pathways to P arkinson's disease

12 Oct 2013

Abstract excerpt

Mitochondria are essential for cellular function due to their role in ATP production, calcium homeostasis and apoptotic signalling. Neurons are heavily reliant on mitochondrial integrity for their complex signalling, plasticity and excitability properties, and to ensure cell survival over decades. The maintenance of a pool of healthy mitochondria that can meet the bioenergetic demands of a neuron, is therefore of...

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PMID: 24117181
DOI: 10.1111/bph.12433

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