Article
Mitochondria: A Therapeutic Target for Parkinson's Disease?
International journal of molecular sciences - 1 Sept 2015
Luo Yu, Hoffer Alan, Hoffer Barry, Qi Xin
Abstract excerpt
Parkinson's disease (PD) is one of the most common neurodegenerative disorders. The exact causes of neuronal damage are unknown, but mounting evidence indicates that mitochondrial-mediated pathways contribute to the underlying mechanisms of dopaminergic neuronal cell death both in PD patients and in PD animal models. Mitochondria are organized in a highly dynamic tubular network that is continuously reshaped by...
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