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Article

Impaired mitochondrial dynamics and function in the pathogenesis of Parkinson's disease.

Experimental neurology - 1 Aug 2009

Büeler Hansruedi

Abstract excerpt

Parkinson's disease (PD), the most frequent movement disorder, is caused by the progressive loss of the dopamine neurons within the substantia nigra pars compacta (SNc) and the associated deficiency of the neurotransmitter dopamine in the striatum. Most cases of PD occur sporadically with unknown cause, but mutations in several genes have been linked to genetic forms of PD (alpha-synuclein, Parkin, DJ-1, PINK1,...

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Source

Identifiers

PMID: 19303005
DOI: 10.1016/j.expneurol.2009.03.006

Genes

PINK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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