Article
A new correlation clustering method for cancer mutation analysis.
Bioinformatics (Oxford, England) - 15 Dec 2016
Hou Jack P, Emad Amin, Puleo Gregory J, Ma Jian, Milenkovic Olgica
Abstract excerpt
MOTIVATION: Cancer genomes exhibit a large number of different alterations that affect many genes in a diverse manner. An improved understanding of the generative mechanisms behind the mutation rules and their influence on gene community behavior is of great importance for the study of cancer. RESULTS: To expand our capability to analyze combinatorial patterns of cancer alterations, we developed a rigorous...
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