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Article

Identification of mutated core cancer modules by integrating somatic mutation, copy number variation, and gene expression data.

BMC systems biology - 1 Jan 2013

Zhang Junhua, Zhang Shihua, Wang Yong, Zhang Xiang-Sun

Abstract excerpt

MOTIVATION: Understanding the molecular mechanisms underlying cancer is an important step for the effective diagnosis and treatment of cancer patients. With the huge volume of data from the large-scale cancer genomics projects, an open challenge is to distinguish driver mutations, pathways, and gene sets (or core modules) that contribute to cancer formation and progression from random passengers which accumulate...

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Identifiers

PMID: 24565034
DOI: 10.1186/1752-0509-7-S2-S4
PMCID: PMC3851989

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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