Article
Genome-wide association study identifies 14 novel risk alleles associated with basal cell carcinoma.
Nature communications - 19 Aug 2016
Chahal Harvind S, Wu Wenting, Ransohoff Katherine J, Yang Lingyao, Hedlin Haley, Desai Manisha, Lin Yuan, Dai Hong-Ji, Qureshi Abrar A, Li Wen-Qing, Kraft Peter, Hinds David A, Tang Jean Y, Han Jiali, Sarin Kavita Y
Abstract excerpt
Basal cell carcinoma (BCC) is the most common cancer worldwide with an annual incidence of 2.8 million cases in the United States alone. Previous studies have demonstrated an association between 21 distinct genetic loci and BCC risk. Here, we report the results of a two-stage genome-wide association study of BCC, totalling 17,187 cases and 287,054 controls. We confirm 17 previously reported loci and identify 14...
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