Article
Multi-ancestry genome-wide meta-analysis identifies novel basal cell carcinoma loci and shared genetic effects with squamous cell carcinoma.
Communications biology - 5 Jan 2024
Choquet Hélène, Jiang Chen, Yin Jie, Kim Yuhree, Hoffmann Thomas J, Jorgenson Eric, Asgari Maryam M
Abstract excerpt
Basal cell carcinoma (BCC) is one of the most common malignancies worldwide, yet its genetic determinants are incompletely defined. We perform a European ancestry genome-wide association (GWA) meta-analysis and a Hispanic/Latino ancestry GWA meta-analysis and meta-analyze both in a multi-ancestry GWAS meta-analysis of BCC, totaling 50,531 BCC cases and 762,234 controls from four cohorts (GERA, Mass-General...
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