Article
Association between genetic variation within vitamin D receptor-DNA binding sites and risk of basal cell carcinoma.
International journal of cancer - 1 May 2017
Lin Yuan, Chahal Harvind S, Wu Wenting, Cho Hyunje G, Ransohoff Katherine J, Dai Hongji, Tang Jean Y, Sarin Kavita Y, Han Jiali
Abstract excerpt
An increasing number of studies have reported a protective association between vitamin D and cancer risk. The vitamin D endocrine system regulates transcriptional programs involved in inflammation, cell growth and differentiation through the binding of vitamin D receptor (VDR) to specific VDR elements. However, limited attention has been given to the role of variation within VDR binding sites in the development...
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