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Article

The mutational spectrum of FOXA2 in endometrioid endometrial cancer points to a tumor suppressor role.

Gynecologic oncology - 1 Nov 2016

Smith B, Neff R, Cohn D E, Backes F J, Suarez A A, Mutch D G, Rush C M, Walker C J, Goodfellow P J

Abstract excerpt

BACKGROUND: Forkhead box protein A2 (FOXA2) plays an important in development, cellular metabolism and tumorigenesis. The Cancer Genome Atlas (TCGA) identified a modest frequency of FOXA2 mutations in endometrioid endometrial cancers (EEC). The current study sought to determine the relationship between FOXA2 mutation and clinicopathologic features in EEC and FOXA2 expression. METHODS: Polymerase chain reaction...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27538367
DOI: 10.1016/j.ygyno.2016.08.237
PMCID: PMC5077662

Genes

FOXA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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