Article
Genome-wide association study of endometrial cancer in E2C2.
Human genetics - 1 Feb 2014
De Vivo Immaculata, Prescott Jennifer, Setiawan Veronica Wendy, Olson Sara H, Wentzensen Nicolas, Attia John, Black Amanda, Brinton Louise, Chen Chu, Chen Constance, Cook Linda S, Crous-Bou Marta, Doherty Jennifer, Dunning Alison M, Easton Douglas F, Friedenreich Christine M, Garcia-Closas Montserrat, Gaudet Mia M, Haiman Christopher, Hankinson Susan E, Hartge Patricia, Henderson Brian E, Holliday Elizabeth, Horn-Ross Pamela L, Hunter David J, Le Marchand Loic, Liang Xiaolin, Lissowska Jolanta, Long Jirong, Lu Lingeng, Magliocco Anthony M, McEvoy Mark, O'Mara Tracy A, Orlow Irene, Painter Jodie N, Pooler Loreall, Rastogi Radhai, Rebbeck Timothy R, Risch Harvey, Sacerdote Carlotta, Schumacher Fredrick, Scott Rodney J, Sheng Xin, Shu Xiao-ou, Spurdle Amanda B, Thompson Deborah, Vanden Berg David, Weiss Noel S, Xia Lucy, Xiang Yong-Bing, Yang Hannah P, Yu Herbert, Zheng Wei, Chanock Stephen, Kraft Peter
Abstract excerpt
Endometrial cancer (EC), a neoplasm of the uterine epithelial lining, is the most common gynecological malignancy in developed countries and the fourth most common cancer among US women. Women with a family history of EC have an increased risk for the disease, suggesting that inherited genetic factors play a role. We conducted a two-stage genome-wide association study of Type I EC. Stage 1 included 5,472 women...
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