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BRCA1 and BRCA2 mutation testing in Cyprus; a population based study.

Clinical genetics - 1 Apr 2017

Loizidou M A, Hadjisavvas A, Pirpa P, Spanou E, Delikurt T, Tanteles G A, Daniel M, Kountourakis P, Malas S, Ioannidis G, Zouvani I, Kakouri E, Papamichael D, Marcou Y, Anastasiadou V, Kyriacou K

Abstract excerpt

This paper presents the largest study in Cyprus evaluating the frequency and distribution of BRCA1/2 mutations in a high risk patient cohort. Deleterious mutations in the BRCA1/2 genes were identified in 68 of the 527 patients tested (13%). It is of interest that a quarter of those tested positive, did not have an extensive family history of breast/ovarian cancer but were diagnosed with early onset breast cancer,...

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Source

Identifiers

PMID: 27882536
DOI: 10.1111/cge.12886

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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