Article
Lack of association between ABO, PPAP2B, ADAMST7, PIK3CG, and EDNRA and carotid intima-media thickness, carotid plaques, and cardiovascular disease in patients with rheumatoid arthritis.
Mediators of inflammation - 1 Jan 2014
López-Mejías Raquel, Genre Fernanda, García-Bermúdez Mercedes, Ubilla Begoña, Castañeda Santos, Llorca Javier, González-Juanatey Carlos, Corrales Alfonso, Miranda-Filloy José A, Pina Trinitario, Gómez-Vaquero Carmen, Rodríguez-Rodríguez Luis, Fernández-Gutiérrez Benjamín, Balsa Alejandro, Pascual-Salcedo Dora, López-Longo Francisco J, Carreira Patricia, Blanco Ricardo, Martín Javier, González-Gay Miguel A
Abstract excerpt
INTRODUCTION: Rheumatoid arthritis (RA) is a polygenic disease associated with accelerated atherosclerosis and increased cardiovascular (CV) mortality. Recent studies have identified the ABO rs579459, PPAP2B rs17114036, and ADAMTS7 rs3825807 polymorphisms as genetic variants associated with coronary artery disease and the PIK3CG rs17398575 and EDNRA polymorphisms as the most significant signals related...