Lack of association between the CXCL12 rs501120 polymorphism and cardiovascular disease in Spanish patients with rheumatoid arthritis.

doi:10.1016/j.humimm.2012.02.012

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Article

Lack of association between the CXCL12 rs501120 polymorphism and cardiovascular disease in Spanish patients with rheumatoid arthritis.

Human immunology - 1 May 2012

López-Mejías Raquel, García-Bermúdez Mercedes, González-Juanatey Carlos, Castañeda Santos, Miranda-Filloy José A, Gómez-Vaquero Carmen, Fernández-Gutiérrez Benjamín, Balsa Alejandro, Pascual-Salcedo Dora, Blanco Ricardo, González-Álvaro Isidoro, Llorca Javier, Martín Javier, González-Gay Miguel A

Abstract excerpt

Rheumatoid arthritis (RA) is an inflammatory disease associated with accelerated atherosclerosis. CXCL12 is a strong chemotactic signal for lymphocytes. Because previous genome-wide association studies demonstrated an association between CXCL12 rs501120 and coronary artery disease, in the present study we assessed the potential association of this polymorphism with the risk of cardiovascular (CV) disease in 1,321...

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Identifiers

PMID: 22386691
DOI: 10.1016/j.humimm.2012.02.012

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CXCL12

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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