Article
Genomic complexity of multiple myeloma and its clinical implications.
Nature reviews. Clinical oncology - 1 Feb 2017
Manier Salomon, Salem Karma Z, Park Jihye, Landau Dan A, Getz Gad, Ghobrial Irene M
Abstract excerpt
Multiple myeloma (MM) is a genetically complex disease that evolves from pre-malignant stages, such as monoclonal gammaopathy of undetermined significance and smouldering multiple myeloma, and progresses to symptomatic MM; this continuum provides a unique framework to study the sequential genomic evolution of MM. In the past 5 years, results from large-scale whole-exome sequencing studies have provided new...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.