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Article

The Genetic Architecture of Multiple Myeloma

1 Jan 2014

Abstract excerpt

Multiple myeloma is a malignant proliferation of monoclonal plasma cells leading to clinical features that include hypercalcaemia, renal dysfunction, anaemia, and bone disease (frequently referred to by the acronym CRAB) which represent evidence of end organ failure. Recent evidence has revealed myeloma to be a highly heterogeneous disease composed of multiple molecularly-defined subtypes each with varying...

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PMID: 24803933
DOI: 10.1155/2014/864058

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