Article
Genomics of Multiple Myeloma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Mar 2017
Robiou du Pont Sebastien, Cleynen Alice, Fontan Charlotte, Attal Michel, Munshi Nikhil, Corre Jill, Avet-Loiseau Hervé
Abstract excerpt
Multiple myeloma (MM) is characterized by wide variability in the chromosomal/genetic changes present in tumor plasma cells. Genetically, MM can be divided into two groups according to ploidy and hyperdiploidy versus nonhyperdiploidy. Several studies in gene expression profiling attempted to identify subentities in MM without convincing results. These studies mostly confirmed the cytogenetic data and...
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