Article
Telomeric RNAs are essential to maintain telomeres.
Nature communications - 17 Aug 2016
Montero Juan José, López de Silanes Isabel, Graña Osvaldo, Blasco Maria A
Abstract excerpt
Telomeres are transcribed generating long non-coding RNAs known as TERRA. Deciphering the role of TERRA has been one of the unsolved issues of telomere biology in the past decade. This has been, in part, due to lack of knowledge on the TERRA loci, thus preventing functional genetic studies. Here, we describe that long non-coding RNAs with TERRA features are transcribed from the human 20q and Xp subtelomeres....
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