Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin

12 Apr 2018

Abstract excerpt

TERRAs are long non-coding RNAs generated from the telomeres. Lack of TERRA knockout models has hampered understanding TERRAs' functions. We recently identified chromosome 20q as one of the main origins of human TERRAs, allowing us to generate the first 20q-TERRA knockout models and to demonstrate that TERRAs are essential for telomere length maintenance and protection. Here, we use ALT 20q-TERRA knockout cells...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to MicroRNA in disease regulation
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29670078
DOI: 10.1038/s41467-018-03916-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatinPMID 29670078Read ↗

Telomeric RNAs are essential to maintain telomeres.Semantic proximity Read ↗

Functional characterization of the TERRA transcriptome at damaged telomeresSemantic proximity Read ↗

Role of TERRA in the Regulation of Telomere LengthSemantic proximity Read ↗

The Emerging Roles of TERRA in Telomere Maintenance and Genome StabilitySemantic proximity Read ↗

Identification of Novel Modulators of the ALT Pathway Through a Native FISH-Based Optical ScreenSemantic proximity Read ↗

TERRA long noncoding RNA: At the interphase of telomere damage, rescue and signalingSemantic proximity Read ↗

Telomeric repeat-containing RNA TERRA: a noncoding RNA connecting telomere biology to genome integritySemantic proximity Read ↗

Expression and differential regulation of human TERRA at several chromosome endsSemantic proximity Read ↗

Identification of TERRA locus unveils a telomere protection role through association to nearly all chromosomesSemantic proximity Read ↗

TERRA ONTseq: a long-read-based sequencing pipeline to study the human telomeric transcriptomeSemantic proximity Read ↗

CpG-island promoters drive transcription of human telomeresSemantic proximity Read ↗

TERRA and the alternative lengthening of telomeres: a dangerous affairSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.