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TERRA long noncoding RNA: At the interphase of telomere damage, rescue and signaling

28 Sept 2024

Abstract excerpt

TERRA long noncoding RNAs play key roles in telomere function and maintenance. They can orchestrate telomeric chromatin remodeling, regulate telomere maintenance by telomerase and homology-directed repair, and they participate in the telomeric DNA damage response. TERRA associates with chromosome ends through base-pairing forming R-loops, which are mediated by the RAD51 DNA recombinase and its partner RAD51AP1....

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Cytomegalovirus and herpesvirus research
RNA regulation and disease
Telomeres, Telomerase, and Senescence

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39342869
DOI: 10.1016/j.ceb.2024.102437

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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