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Article

Telomeric repeat-containing RNA TERRA: a noncoding RNA connecting telomere biology to genome integrity

14 Apr 2015

Abstract excerpt

Telomeres are dynamic nucleoprotein structures that protect the ends of chromosomes from degradation and activation of DNA damage response. For this reason, telomeres are essential to genome integrity. Chromosome ends are enriched in heterochromatic marks and proper organization of telomeric chromatin is important to telomere stability. Despite their heterochromatic state, telomeres are transcribed giving rise to...

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Identifiers

PMID: 25926849
DOI: 10.3389/fgene.2015.00143

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Telomeric repeat-containing RNA TERRA: a noncoding RNA connecting telomere biology to genome integrityPMID 25926849Read ↗

The Emerging Roles of TERRA in Telomere Maintenance and Genome StabilitySemantic proximity Read ↗

Role of TERRA in the Regulation of Telomere LengthSemantic proximity Read ↗

TElomeric repeat-containing RNA (TERRA): Physiological functions and relevance in cancerSemantic proximity Read ↗

TERRA long noncoding RNA: At the interphase of telomere damage, rescue and signalingSemantic proximity Read ↗

R-Loops at Chromosome Ends: From Formation, Regulation, and Cellular ConsequenceSemantic proximity Read ↗

Telomeric Noncoding RNA TERRA Is Induced by Telomere Shortening to Nucleate Telomerase Molecules at Short TelomeresSemantic proximity Read ↗

TERRA and the alternative lengthening of telomeres: a dangerous affairSemantic proximity Read ↗

Regulated expression of the lncRNA TERRA and its impact on telomere biology.Semantic proximity Read ↗

A practical qPCR approach to detect TERRA, the elusive telomeric repeat-containing RNASemantic proximity Read ↗

The RNA-binding motif protein 14 regulates telomere integrity at the interface of TERRA and telomeric R-loopsSemantic proximity Read ↗

Functional characterization of the TERRA transcriptome at damaged telomeresSemantic proximity Read ↗

BRCA1 binds TERRA RNA and suppresses R-Loop-based telomeric DNA damage.Semantic proximity Read ↗

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