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Article

Role of TERRA in the Regulation of Telomere Length

1 Jan 2015

Abstract excerpt

Telomere dysfunction is closely associated with human diseases such as cancer and ageing. Inappropriate changes in telomere length and/or structure result in telomere dysfunction. Telomeres have been considered to be transcriptionally silent, but it was recently demonstrated that mammalian telomeres are transcribed into telomeric repeat-containing RNA (TERRA). TERRA, a long non-coding RNA, participates in the...

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PMID: 25678850
DOI: 10.7150/ijbs.10528

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Role of TERRA in the Regulation of Telomere LengthPMID 25678850Read ↗

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