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Article

Instrumental variable analysis of multiplicative models with potentially invalid instruments.

Statistics in medicine - 20 Dec 2016

Shardell Michelle, Ferrucci Luigi

Abstract excerpt

Instrumental variable (IV) methods have potential to consistently estimate the causal effect of an exposure on an outcome in the presence of unmeasured confounding. However, validity of IV methods relies on strong assumptions, some of which cannot be conclusively verified from observational data. One such assumption is that the effect of the proposed instrument on the outcome is completely mediated by the...

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PMID: 27527517
DOI: 10.1002/sim.7069
PMCID: PMC5118169

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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