Article
Knockout of Abi3bp in mice does not affect their olfactory function, mental state and NNK-induced lung tumorigenesis.
Acta biochimica et biophysica Sinica - 1 Sept 2016
Yang Hua, Chen Weidong, Shi Jiahao, Huang Dandan, Li Jun, Hu Binyang, Zhang Mengjie, Wang Zhugang, Fei Jian
Abstract excerpt
Abi3bp was originally discovered as Abi3-Src homology 3 (SH3) binding protein and has been proved to have a broad expression profile in adult tissues. Although previous studies have indicated that Abi3bp may be associated with cancer suppression, cell senescence, dendritic refinement and mental disorder, most conclusions achieved were based on in vitro model or genome-wide association study. In this work, we...
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