Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comparative fluxome and metabolome analysis for overproduction of succinate in Escherichia coli.

Biotechnology and bioengineering - 1 Apr 2016

Taymaz-Nikerel Hilal, De Mey Marjan, Baart Gino J E, Maertens Jo, Foulquié-Moreno Maria Remedios, Charlier Daniel, Heijnen Joseph J, van Gulik Walter M

Abstract excerpt

An aerobic succinate-producing Escherichia coli mutant was compared to its wild-type by quantitatively analyzing both the metabolome and fluxome, during glucose-limited steady-state and succinate excess dynamic conditions, in order to identify targets for further strain engineering towards more efficient succinate production. The mutant had four functional mutations under the conditions investigated: increased...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aerobiosis
Share to Escherichia coli

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Metabolome

Share to Mutation

Share to Succinic Acid

Source

Identifiers

PMID: 26444867
DOI: 10.1002/bit.25850

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparative fluxome and metabolome analysis for overproduction of succinate in Escherichia coli.PMID 26444867Read ↗

Metabolic engineering of Escherichia coli and in silico comparing of carboxylation pathways for high succinate productivity under aerobic conditions.Semantic proximity Read ↗

High-yield anaerobic succinate production by strategically regulating multiple metabolic pathways based on stoichiometric maximum in Escherichia coli.Semantic proximity Read ↗

Chemostat culture characterization of Escherichia coli mutant strains metabolically engineered for aerobic succinate production: a study of the modified metabolic network based on metabolite profile, enzyme activity, and gene expression profile.Semantic proximity Read ↗

Characterization of E. coli MG1655 and frdA and sdhC mutants at various aerobiosis levels.Semantic proximity Read ↗

Metabolic evolution of energy-conserving pathways for succinate production in Escherichia coli.Semantic proximity Read ↗

Effect of growth phase feeding strategies on succinate production by metabolically engineered Escherichia coli.Semantic proximity Read ↗

Directed pathway evolution of the glyoxylate shunt in Escherichia coli for improved aerobic succinate production from glycerol.Semantic proximity Read ↗

Metabolic analysis of Corynebacterium glutamicum during lactate and succinate productions under oxygen deprivation conditions.Semantic proximity Read ↗

Model-aided atpE gene knockout strategy in Escherichia coli for enhanced succinic acid production from glycerol.Semantic proximity Read ↗

High yield production of four-carbon dicarboxylic acids by metabolically engineered Escherichia coli.Semantic proximity Read ↗

Industrial systems biology of Saccharomyces cerevisiae enables novel succinic acid cell factory.Semantic proximity Read ↗

Genome-scale analysis of Mannheimia succiniciproducens metabolism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.