Article
Industrial systems biology of Saccharomyces cerevisiae enables novel succinic acid cell factory.
PloS one - 1 Jan 2013
Otero José Manuel, Cimini Donatella, Patil Kiran R, Poulsen Simon G, Olsson Lisbeth, Nielsen Jens
Abstract excerpt
Saccharomyces cerevisiae is the most well characterized eukaryote, the preferred microbial cell factory for the largest industrial biotechnology product (bioethanol), and a robust commerically compatible scaffold to be exploitted for diverse chemical production. Succinic acid is a highly sought after added-value chemical for which there is no native pre-disposition for production and accmulation in S. cerevisiae....
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