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Article

Association of DNA repair and steroid metabolism gene polymorphisms with clinical late toxicity in patients treated with conformal radiotherapy for prostate cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Apr 2006

Damaraju Sambasivarao, Murray David, Dufour Jennifer, Carandang Diana, Myrehaug Sten, Fallone Gino, Field Colin, Greiner Russell, Hanson John, Cass Carol E, Parliament Matthew

Abstract excerpt

OBJECTIVE: To explore the possible relationship between single nucleotide polymorphisms (SNP) in candidate genes encoding DNA damage recognition/repair/response and steroid metabolism proteins with respect to clinical radiation toxicity in a retrospective cohort of patients previously treated with three-dimensional conformal radiotherapy (3-DCRT) for prostate cancer. EXPERIMENTAL DESIGN: One hundred twenty-four...

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BRCA2 Protein
DNA Ligase ATP
DNA Ligases
Radiotherapy Dosage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Urinary Bladder

Xeroderma Pigmentosum Group D Protein

Source

Identifiers

PMID: 16638864
DOI: 10.1158/1078-0432.CCR-05-2703

Genes

LIG4
ERCC2
XRCC3
ATM
BCL2
BRCA1
BRCA2
ESR1
MLH1
MSH6
NBN
RAD51
RAD52
TGFB1
XRCC1
XRCC2

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